Australian Physiological Society

Helen Inkson and APAC Scientific has kindly offered individual rehearsal slots for students and will give up to 30 minutes per student. Please e-mail Helen at hinkson@apacscientific.com to book a session. The allotted time allows for tailored feedback and is a fantastic opportunity for students to refine their talks and ensure they are punchy and engaging!

Session 1 - 09.00

	Chairs: Prof Lea Delbridge and Dr Pratik Thakkar	Room CR1
9.00	Mechanisms contributing to impaired glucose oxidation in diabetic cardiomyopathy	Dr John Ussher University of Alberta	SS1
9.30	Winner of the Physiological Society of NZ Early Career Award GLP1 receptor agonist ameliorates high blood pressure and high blood sugar in a rat model of "glucotension"	Dr Pratik Thakkar University of Auckland	SS2
10.00	Sugar mishandling in diabetic heart disease	A/Prof Kim Mellor University of Auckland	SS3
10.30	Novel targets and therapies for cardiometabolic disease	Dr Bianca Bernardo Deakin University	SS4

	Chair: A/Prof Adam Rose	Room CR3/4
9.00	Systems Physiology of Insulin Resistance and Type 2 Diabetes	Prof David James University of Sydney	SS5
9.30	Discovery of genetic and tissue-specific determinants of metabolic control using diversity outbred mice	Dr Jaqueline Stoeckli University of Sydney	SS6
10.00	A Systems Genetic Analysis of the Cardiac Response to Exercise in Male and Female Hybrid Mouse Lines	Prof Brian Drew Baker Heart and Diabetes Institute	SS7
10.30	Physiological determinants of the variability in glucose and insulin responses to glucose feeding in young adults	A/Prof Chris Shaw Deakin University	SS8

Morning Tea 11.00-11.30

Session 2 - 11.30

	Chair: Prof Livia Hool	Room CR1
11.30	GABAB receptor regulation of membrane excitability and modulation of ion channels in human pluripotent stem cell-derived sensory neurons (hPSCs)	Arsalan Yousuf University of Sydney	FC8
11.45	Paradoxical role of TRPC1/4 channels in the regulation of uterine contractility during pregnancy and in labour	Karen Q.W. Leow Monash University	FC9
12.00	Harnessing uterine potassium channels to improve labour outcomes for women	Helena C Parkington Monash University	FC10
12.15	An electrophysiological assay to study the diverse functional properties of pathogenic CACNA1A variants	Cameron Adly University of Sydney	FC11
12.30	Fractional anisotropy measured from Diffusion Tensor MRI identifies neuroprotection in a severe traumatic brain injury rat model with the first-in-class TRPC channel blocker Xolatryp™	Georg von Jonquieres UNSW	FC12
12.45	Targeted drug screening in a Drosophila model of KCNT1 epilepsy	Rashid Hussain University of South Australia	FC13
13.00	Help or hinderance, are CryoEM structures sufficient evidence for precision medicine in epilepsy?	Anushka Goswami Western Sydney University	FC14
13.15	Different actions of RyR2 open and closed channel block explained by a multiscale Ca2+ release model	Derek Laver University of Newcastle	FC15

	Chair: Dr Craig Goodman	Room CR3/4
11.30	Unravelling the role of the deubiquitinase Ubiquitin-Specific-Protease-15 (USP15) in skeletal muscle	Wayne Du University of Melbourne	FC1
11.45	Investigations into the Regulation and Role of Methyltransferase 21C in Skeletal Muscle	Scott Carter University of Melbourne	FC2
12.00	The Contribution of Sex Hormones in Muscle Mass, Function, and Molecular Signalling in Females Aged 18-80	Annabel J Chritchlow Deakin University	FC3
12.15	Endogenous testosterone is associated with skeletal muscle fibre composition, but not muscle size or strength in males	Ross Williams Deakin University	FC4
12.30	Unravelling how biological sex and sex hormones shape the human muscle transcriptome across the lifespan	Karel Van Belleghem Deakin University	FC5
12.45	Age related skeletal muscle and metabolic changes in response to a 3.5 day fast	Eloise K Tarry University of Copenhagen	FC6
13.00	Role of exercise-derived extracellular vesicles in regulating mitochondrial responses in skeletal muscle	Paula M Miotto University of Melbourne	FC7

Lunch 13.30-14.45

ECR Workshop - 13:40

Not sure where your career is supposed to be heading? Wondering where to go now? We are honoured to present Dr Darren Saunders from the Office of the Chief Scientist to speak at the this year's ECR workshop. Dr Saunders has followed both the traditional academic career path and then detoured to a prominent role in science communication. Join for some invaluable advice and the opportunity to network with peers from around the country

Session 3 - 14.45

	Chair: Dr Kayte Jenkins	Room CR1
14.30	Molecular control of hepatic ureagenesis with dietary protein enrichment	Adam J Rose Monash University	FC16
14.45	The Secondary bile acid Taurodeoxycholic acid may predict, but paradoxically arrest the progression of, hepatocellular carcinoma	Benoit Smeuninx Monash University	FC17
15.00	The role of activin A in renal and skeletal muscle pathophysiology in kidney disease	Alexandra Walker Western Sydney University	FC18
15.15	The multi-omic mosaic of spiral ganglion neuron subpopulation distributions	Lily Pearson UNSW	FC19
15.30	Genetic mapping of the morphological and proteomic landscapes of adipose tissue reveals novel ECM – adipocyte interactions	Aaron M Lambert University of Sydney	FC20
15.45	Molecular Insights into Regional Retinal Physiology: A Multi-Omics Approach to Macula-Periphery Features	Azhar Dzulhadi B Arafah University of Sydney	FC21

Free Communications: We are all in this together

Integrated Physiology

	Chair: Brad Launikonis	Room CR3/4
14.30	Regulation of muscle contractile function by local and distant adipose tissue	A/Prof. Gretchen Meyer University of Washington	SS9
15.00	Modulating myogenesis using natural bioactive compounds	Dr Marissa Caldow University of Melbourne	SS10
15.30	Muscling into Reproduction: Emerging evidence for myokine influences on reproductive systems	Dr Kelly Walton University of Queensland	SS11
16.00	Ca2+ regulates the acute response to sprint interval exercise in human muscle	Prof. Brad Launikonis University of Queensland	SS12

Afternoon Tea 16.45

ECR Mixer - 17.30

The ECR mixer will be at the at Ruse Bar, located across the road from the conference,the address is 4 Parramatta Square.

AuPS would like to thank our meeting sponsors

AuPS is incorporated in Victoria, Australia Registration No. A0021266A | ABN 65 820 412 570